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I have been thinking a lot lately about “diachronic AI” and “vintage LLMs” — language models designed to index a particular slice of historical sources rather than to hoover up all data available. I’ll have more to say about this in a future post, but one thing that came to mind while writing this one is the point made by AI safety researcher Owain Evans about how such models could be trained:
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Онкологи призывают россиян регулярно проходить чек-апы.Какие недорогие методы раннего обнаружения заболевания существуют сегодня?5 февраля 2026
从1994年 FGFR3靶点被证实与ACH相关，到2021年Vosoritide获批上市，ACH患者等待了近30年，才迎来首款针对性治疗药物。而随着Infigratinib叩响上市的大门，以及身后一众迭代疗法的逼近，ACH精准治疗的新大门正加速开启。这也是罕见病从被行业忽略到逐渐被重视的真实缩影。
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